Symptom and Age Homophilies in SARS-CoV-2 Transmission Networks during the Early Phase of the Pandemic in Japan

Kanagawa and Hokkaido were affected by COVID-19 in the early stage of pandemic. Japan’s initial response included contact tracing PCR analysis on anyone who was suspected having been exposed to SARS-CoV-2. In this retrospective study, we analyzed publicly available registry data from (n = 4392). Exponential random graph model (ERGM) network performed examine demographic symptomological homophilies. Age, symptomatic, asymptomatic status homophilies seen both prefectures. Symptom suggest that nuanced genetic differences virus may affect its epithelial cell type range can result diversity symptoms individuals infected Environmental variables such as temperature humidity also play a role overall pathogenesis virus. A higher level transmission observed Kanagawa. Moreover, patients contracted through secondary or tertiary contacts shown be more frequently than those it primary cases. Additionally, most transmissions stopped at levels. As expected, significant viral healthcare settings.